WebOriginally characterized as angiogenic factors, fibroblast growth factors (FGFs) are pleiotropic factors that exert autocrine and paracrine functions on tumor and stromal … WebApr 14, 2024 · PDF Hyperphosphatemic familial tumoral calcinosis (HFTC) is a rare, inherited autosomal recessive disorder caused by fibroblast growth factor-23... Find, read and cite all the research you ...
FGF-23 in fibrous dysplasia of bone and its relationship to renal ...
FGF23 (fibroblast growth factor 23) inhibits phosphate transport in the renal tubule and reduces calcitriol production by the kidney. Tumor production of FGF23, Secreted frizzled-related protein 4 and matrix extracellular phosphoglycoprotein (MEPE) have all been identified as possible causative agents for the hypophosphatemia. WebMay 18, 2024 · FGF23 is a hormone secreted mainly by osteocytes and osteoblasts in bone. Its pivotal role concerns the maintenance of mineral ion homeostasis. It has been confirmed that phosphate and vitamin D metabolisms are related to the effect of FGF23 and its excess or deficiency leads to various hereditary diseases. britten close aldeburgh
Hypophosphatemia and FGF23 tumor-induced osteomalacia in …
WebApr 11, 2024 · Request PDF On Apr 11, 2024, Naoya Fujita and others published Scintigraphic Findings in FGF23-related Hypophosphatemic Osteomalacia Find, read and cite all the research you need on ResearchGate WebApr 13, 2024 · Notably, TGF-β1 and fibroblast growth factor (FGF) cause opposing regulation of CAF effector genes, demonstrating that various activation approaches may result in various CAF phenotypes, with... WebFGF23 is overexpressed in prostate cancer tissues and studies in prostate cancer cell lines have shown that it acts as an autocrine, paracrine, and/or endocrine growth factor [ 10 ]. Whereas exogenous FGF23 enhanced proliferation, invasion, and anchorage-independent growth in vitro, FGF23 knockdown decreased these phenotypes. captain morgan private stock abc