WebAug 13, 2024 · Glut2 is expressed in neurons, astrocytes, oligodendrocytes, ependymal cells, and tanycytes (Tables 2 and 3) [12, 13, 24, 83, 132, 230, 245, 258, 294]. Glut2 is supposed to be involved in … WebObjective: Glucose transporter 2 (GLUT2) is expressed in the pancreatic β-cell, intestine, liver, and kidney in mice. Although GLUT2 is considered as a major regulator of insulin secretion, in vivo contribution of β-cell Glut2 to glucose-stimulated insulin secretion and systemic glucose homeostasis is undefined. Therefore, the main objective of this study is …
GLUT 2: characteristics, structure, functions - science - 2024
WebApr 5, 2024 · Data were expressed ± SEM from three independent experiments (n = 3). e The ... At the transcription level, we found the mRNA levels of crucial genes for β cell function and survival, such as PDX1, Glut2, Insulin1, and NKX6.1, were restored in MIN6 and INS-1 cells with MST1 suppression in high-glucose condition. Meanwhile, ... WebDec 16, 2006 · Flavonoid inhibition of GLUT2 expressed in cRNA-injected Xenopus laevis oocytes. We first investigated whether flavonoids inhibited transport of one or both of the two major substrates for GLUT2: fructose and glucose. Transport was studied using Xenopus oocytes injected with human GLUT2 cRNA as a specific expression system. lock and store basingstoke
GLUT2, glucose sensing and glucose homeostasis
WebGLUT2 was expressed only in the liver and kidney. GLUT3 was highly expressed in the brain. GLUT8 was expressed ubiquitously, with expression in kidney and adipose tissue relatively higher than that of other tissues. 3. Expression levels of GLUT isoforms 1, 3 and 8 in skeletal muscle tissue were very low compared to the other tissues tested. WebJul 2, 2024 · GLUT2 ∆loopS_Q455R recapitulates the functional properties of GLUT2 closely. For example, GLUT2 expressed in Xenopus laevis oocytes had K M, Glucose = … WebMar 24, 2024 · Glucose transporter 2 (glut2) has been studied in mammals, aves, and several fish, while the comparative studies of glut2 in common carp are still lacking. In this study, glut2 was firstly isolated and characterized from the liver of common carp. The full-length cDNA of glut2 was 2351 bp with an open reading frame (ORF) of 1512 bp, … lock and store longwell green